Bubble Study

Bubble Study (agitated saline contrast study)

A bubble study is a specialised form of echocardiogram used to detect abnormal blood flow between the heart’s chambers, most commonly to identify a patent foramen ovale (PFO)—a small opening between the upper chambers of the heart that may not have closed after birth. 

During the test, a saline solution mixed with a small amount of air is injected into a vein, creating tiny bubbles. These bubbles travel to the right side of the heart and are tracked via ultrasound. If bubbles appear on the left side of the heart, it may indicate a PFO or other abnormal connection. 

This test is often recommended for patients with: 

  • Unexplained strokes or transient ischemic attacks (TIAs) 
  • Certain congenital heart conditions 

After the Test

You can resume normal activities immediately. Your referring doctor will receive a detailed report, and urgent findings will be communicated promptly. 

Patient Preparation

  • Fasting: No fasting is required. You may eat and drink as normal before the test. 
  • Medications: Continue taking all prescribed medications unless advised otherwise by your doctor. 
  • Clothing: Wear a two-piece outfit. You will be asked to undress to the waist for the echocardiogram. A gown can be provided. 
What to Expect: 
  • A resting echocardiogram may be performed first. 
  • A small IV cannula will be inserted into a vein in your arm. 
  • You may be asked to briefly hold your breath for a moment to enhance the test’s accuracy. 
  • The test is painless and typically takes 30–45 minutes. 

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